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The brain is a heterogeneous porous medium with regions of anisotropy. Measurements of tortuosity (λ) showed that diffusion in gray matter (e.g. striatum) is isotropic (λ = 1.65), whereas it is anisotropic in white matter (e.g. corpus callosum) (λparallel = 1.38, λperpendicular = 1.80) ... Mehr lesen
At the 2006 Winter Olympics, the jump length difference between first and second place was only 5cm. This illustrates why ski jumpers are constantly tinkering with their posture in order to gain even the smallest of advantages. Experiments such as those shown in Figures 1 and 2 (b), ... Mehr lesen
Background: Even though the direct nose-to-brain drug delivery has multiple advantages, its application is limited by the low delivery efficiency (<1%) to the olfactory region with standard nasal devices. Novel delivery techniques are needed that can deliver clinically relevant dosage ... Mehr lesen
REBCO tapes belong to a class of high-temperature superconductors (HTS) that can be superconducting at liquid nitrogen temperatures (77K) as opposed to typical superconductors such as Nb3Sn which need to operate at liquid helium temperatures (4K). One important aspect of designing a ... Mehr lesen
Our inability to record single cell activity with high resolution over a long period of time precludes fundamental understanding of nervous system functions, both under normal and pathological conditions. While the fabrication of current micro- and nano-electrodes has advanced our ... Mehr lesen
We have created and optimized a multiphysics model using COMSOL Multiphysics® software that incorporates the Free and Porous Media Flow and Heat Transfer in Porous Media interfaces to simulate the temperature profile of a chromatographic system under external heating and cooling ... Mehr lesen
Non-communicable diseases (NCDs) have globally become a prevalent problem, accounting for more than 60% of the mortality worldwide. NCDs impose socioeconomic consequences to low-income countries as 80% of NCD deaths occur in such countries [1, 2]. The World Health Organization has ... Mehr lesen
The aim of this paper is to determine the location of the “sweet spot” for a selected cricket bat commonly used in the sport. Knowledge of the “sweet spot” is important in delivering a shot that utilizes the optimal zone of the bat that corresponds to the maximum power of the stroke. A ... Mehr lesen
A simulation was performed to investigate the flow behaviors of drug delivery nanoparticles in a tumor-on-a-chip microfluidic device, which mimics a tumor cell having endothelial cells with micro-sized gaps. The Navier-Stokes equation and the convection-diffusion equation were used to ... Mehr lesen
The isolation of target cells from biological samples such as serum, urine or blood in high-throughput manner without contamination with other cells is the starting point of developing effective therapy for many diseases. Currently available methods for cell isolation/separation require ... Mehr lesen