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Stochastic Diffusion of Calcium Ions Through a Nanopore in the Cell Membrane Created by Electroporation

O. Henao[1], V. Gómez[1], I. De La Pava[1], J. Sánchez [1]
[1]Grupo Fisiología Celular y Aplicada, Universidad Tecnológica de Pereira, Pereira, Risaralda, Colombia

We simulated the diffusion of calcium ions through a nanopore created in the cell membrane by electroporation, in presence and absence of the external electric field responsible of the membrane permeabilization. First we solved the set of coupled differential equations that describe the ... Mehr lesen

Simulation of Normal and Cancerous T-cell Membrane Electroporation

O. Henao[1], V. Gómez[1], I. De la Pava[1], J. Sánchez[1]
[1]Grupo Fisiología Celular y Aplicada, Universidad Tecnológica de Pereira, Pereira, Risaralda, Colombia

Electroporation is an increase of the cell membrane permeability due to the formation of aqueous pores in it when the cell is under the influence of an intense electric field [1][2]. The formation of such pores in the membrane can be used to enhance the uptake of chemotherapeutic drugs ... Mehr lesen

Digital Microfluidic Droplet Adapter for Interconnection of Biochips

R. Zhu[1], X. Xiong[2], P. Patra[1], C. Jin[1], J. Hu[3]
[1]Department of Biomedical Engineering, University of Bridgeport, Bridgeport, CT, USA
[2]Department of Electrical & Computer Engineering, University of Bridgeport, Bridgeport, CT, USA
[3]Department of Mechanical Engineering, University of Bridgeport, Bridgeport, CT, USA

In this research, we use the COMSOL Multiphysics® software to design and simulate a digital microfluidic droplet adapter for board-level biochip integration. Digital Microfluidic Biochip (DMFB) has gained tremendous research interest in recent years due to its importance in Lab-on-a-Chip ... Mehr lesen

Simulations of Heat and Mass Transport During Biomass Conversion Processes Using 3D Biomass Particle Models with Realistic Morphology and Resolved Microstructure

P. Ciesielski[1], M. Crowley[1], L. Thompson[1], B. Donohoe[1], D. Robichaud[2], A. Sanders[3], M. Nimlos[2], T. Foust[2]
[1]Biosciences Center, National Renewable Energy Laboratory, Golden, CO, USA
[2]National Bioenergy Center, National Renewable Energy Laboratory, Golden, CO, USA
[3]Quantum Electronics & Photonics Division, National Institute of Standards & Technology, Boulder, CO, USA

Predictive simulations of biomass conversion processes will improve their technical performance and reduce economic uncertainty surrounding industrialization of biofuels production. The majority of present conversion simulations treat the biomass feedstock with simplifying assumptions ... Mehr lesen

Design of an Automated Thermal Cycler for Long-term Phase Change Material Phase Transition Stability Studies

D. Groulx[1], A. C. Kheirabadi[1]
[1]Mechanical Engineering, Dalhousie University, Halifax, NS, Canada

This paper highlights the use of the COMSOL Multiphysics® software during the design process of a thermal cycling system for regulated PCM phase transitioning. The primary purpose of the simulations was to predict the system behavior in response to an ON/OFF temperature control system ... Mehr lesen

Delamination of Sub-Crustal Lithosphere

P. Vincent[1], E. Humphreys[2]
[1]College of Earth, Ocean, & Atmospheric Sciences, Oregon State University, Corvallis, OR, USA
[2]Department of Geological Sciences, University of Oregon, Eugene, OR, USA

Introduction: Lithospheric delamination beneath the western U.S. is believed to be the driving mechanism responsible for the evolution of magmatic and topographic features observed at the surface in the western U.S.. This process requires hot asthenosphere to be in contact with the ... Mehr lesen

Generating Simulated Data for Spot Heating/IR Camera Analysis of Coal Slag Surfaces

M. Silva[1], T. Ring[1]
[1]Department of Chemical Engineering, University of Utah, Salt Lake City, UT, USA

For combustion simulations, the wall temperature and heat transfer is an important piece of information. Coal combustion systems typically have walls that are initially a cast ceramic, but, with time, slag is deposited on the surface and coal and soot are incorporated into the slag. It ... Mehr lesen

Modeling and Simulation of Dual Application Capacitive MEMS Sensor

A. Ravi[1], R. Krishna[1], J. Christen[1]
[1]Arizona State University, Tempe, AZ, USA

Capacitive MEMS sensors offer high spatial resolution, sensitivity and good frequency response. In this paper, we present a circular membrane capacitive MEMS device that finds use both as capacitive micromachined ultrasonic transducer (CMUT) and pressure sensor. The MEMS device is first ... Mehr lesen

Geomagnetic Modeling with COMSOL Multiphysics® Software

G. Ha[1], S. S. Kim[1], J. H. Kim[1]
[1]Chungnam National University, Daejeon, Korea

Here we aim to advance geomagnetic modeling approaches using COMSOL Multiphysics® software and improve the degree of detail that can be obtained from the measured magnetic field. First, we carried out benchmark tests by comparing the computed results using the widely used analytic ... Mehr lesen

CFD/Electromagnetics Interactions via Realistic Heat and Mass Transfer to Moist Substrates

G. Ruocco[1], M. V. De Bonis[2]
[1]Engineering College, University of Basilicata, Potenza, Italy
[2]Institute of Food Science and Production, National Research Council, Bari, Italy

Localized convection heat and mass transfer can be intensified and optimized by providing exposure to electromagnetic energy. Conjugate heat and mass transfer are configured by solving the momentum, heat and mass transfer simultaneously in both solid (substrate, comprising of a two-phase ... Mehr lesen

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