Simulation of Interstitial Nanoparticle Flow for Development of Tumor-On-A-Chip Device
Veröffentlicht in 2016
A simulation was performed to investigate the flow behaviors of drug delivery nanoparticles in a tumor-on-a-chip microfluidic device, which mimics a tumor cell having endothelial cells with micro-sized gaps. The Navier-Stokes equation and the convection-diffusion equation were used to model the flow field and the time-dependent particle distribution in the device, respectively. We investigated the effect of the drug delivery nanoparticle size on the particle transport from microchannel (mimicking blood stream) into the tumor chamber (tumor cell) through porous arrays (gaps in endothelial cells).
Herunterladen
- park_poster.pdf - 3.31MB
- park_paper.pdf - 1.53MB
- park_abstract.pdf - 0.55MB