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Problem with using intop1

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Hello All,

I am solving a system of PDE's that simulates the accumulation of a protein in response to a force applied at the tip of the geometry (of a cell) . The protein accumulates to the point where force is applied (here to the tip of the geometry) and in response to the applied force it generates a force in the opposite direction (a negative feedback).

To calculate the force from the protein, I first calculate the total number of molecules of the protein available in a particular domain using intop1(Concentration[mol/m^3])*thickness. Here is my problem, when I do intop1(Concentration), for a lower concentration I get a higher mol/m when compared to the mol/m that I get for a higher concentration. The geometry I am using is a 2D geometry, however I dont seem to have any problem with a 2D axis-symmetric geometry when I do intop1(Concentration)*thickness.

Could some one point out what is wrong in my implementation. Because I am not getting the right molecules over a domain in the 2D case, my protein force calculation is wrong and hence the other steps in my model.

And I am using a 4.3 Classkit license.

Best,

Krithika Mohan

0 Replies Last Post 07.04.2014, 17:12 GMT-4
COMSOL Moderator

Hello Krithika Mohan

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